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General Principles of Pharmacology

Presented by Barbara DeMarco

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Physical and Occupational Therapy literature provides limited coverage of medications commonly seen in practice. Additionally, these sources of information provide only superficial coverage of pharmacologic principles and how these relate to therapeutic interventions for our patients. The aim of this series is to present the most common drug categories seen in practice and discuss their interaction with exercise, when applicable. The first course in this series introduces learners to the general principles of pharmacology. Students will also learn how to recognize adverse drug events and to use physical findings to determine toxicity.

Meet your instructor

Barbara DeMarco

Dr. DeMarco (formerly Gladson) is the Senior Associate Dean for Education at the Rutgers University School of Health Professions and is currently co-leading the Workforce Development Core for the New Jersey Alliance for Clinical and Translational Science’s NIH CTSA for Princeton, New Jersey Institute of Technology and Rutgers…

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Chapters & learning objectives

Introduction

1. Introduction

The first chapter of this course provides an introduction to pharmacology. A variety of introductory topics are covered, including the average number of prescriptions filled by elderly individuals in the U.S., and the phases of drug development.

Pharmacokinetics

2. Pharmacokinetics

Pharmacokinetics describes a drug’s concentration in various tissues of a body over time. In Chapter Two, Dr. Barbara Gladson reviews the phases of pharmacokinetics (PK), from absorption until elimination. Dr. Gladson also discusses PK and cardiac disease, PK and liver disease, and PK changes with aging.

Pharmacokinetics and Exercise

3. Pharmacokinetics and Exercise

In Chapter Three, Dr. Barbara Gladson explains the interactions between exercise and pharmacokinetics. She discusses why many drug-exercise studies are flawed and dispels incorrect assumptions regarding pharmacokinetics and exercise.