Duchenne Muscular Dystrophy Part 1: What We Know Now

Presented by Claudia Senesac

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Duchenne Muscular Dystrophy (DMD) is the most common childhood muscular dystrophy. Much of what we have known about this disease has been based on years of clinical observation, muscle biopsy, and other limited testing. Longitudinal studies and clinical trials are shaping our “new understanding” of this disease. The courses related to DMD will span pathophysiology, research, the development of therapy recommendations, and quality of life issues. Therapy recommendations are based on predictive models of biomarkers and function, helping therapists and families plan for the future. Therapists play a critical role in caring for boys and young men with this disease.

Meet your instructor

Claudia Senesac

Claudia Senesac is a clinical associate professor at University of Florida in the Doctor of Physical Therapy department. Her teaching responsibilities include functional anatomy dissection and pediatrics in physical therapy. She has over 37 years of pediatric clinical experience. She has been the owner and administrator of a…

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Chapters & learning objectives

What We Know Now

1. What We Know Now

The chapter will provide foundational background information to enhance the participants' understanding of DMD. Signs and symptoms of this disease will be detailed and the process of differential diagnosis reviewed. The most common medications and supplements will be covered.

Identified Biomarkers

2. Identified Biomarkers

Identified biomarkers have helped to further our understanding of this disease and monitor disease progression. Selected biomarkers have been developed and are emerging as outcome measures in research.

Research and Understanding DMD

3. Research and Understanding DMD

Longitudinal research studies shed light on our current understanding of DMD. Correlations of multiple outcomes help make predictions for function. Predictions of function allow for planning for the future.